USES: This medication is used to treat minor pain, itching, swelling, and discomfort caused by hemorrhoids and other problems of the anal area (such as anal fissures, itching). NA: Information not available.ĬOMMON BRAND NAME(S): Anusol-HC, Proctocream-HC, Proctosol HC Risks involved outweigh potential benefits. D: Use in LIFE-THREATENING emergencies when no safer drug available. Animal studies show risk and human studies not available or neither animal nor human studies done. C: Use with caution if benefits outweigh risks. Either animal studies show no risk but human studies not available or animal studies showed minor risks and human studies done and showed no risk. Controlled studies in pregnant women show no evidence of fetal risk. Not know whether topical administration could result in sufficient systemic absorption to produce detectable quantities in breast milk systemically administered corticosteroids are secreted into breast milk in quantities not likely to have deleterious effect on infant nevertheless, caution should be exercised when topical corticosteroids are administered to a nursing woman Pregnancy CategoriesĪ: Generally acceptable. There are no adequate and well-controlled studies in pregnant women on teratogenic effects from topically applied corticosteroids corticosteroids generally teratogenic in laboratory animals when administered systemically at relatively low dosage levels topical corticosteroids should be used during pregnancy only if potential benefits justify potential risk to fetus should not be used extensively on pregnant patients, in large amounts, or for prolonged periods of time Lactation Use caution in patients with diabetes, cardiovascular disease, hepatic impairment, myocardial infarction, myasthenia gravis, osteoporosis, ocular disease, renal impairment, or thyroid disease Local desensitization (irritation, redness) reported discontinue if it occurs May suppress hypothalamic-pituitary-adrenal axis, especially in patients receiving high doses for prolonged periods of time and younger children, which may result in adrenal crisisĪnaphylactoid reactions reported in patients receiving corticosteroids Psychiatric disturbances including euphoria, insomnia, mood swings, and personality changes reported with corticosteroid useĪllergic contact dermatitis may occur diagnosed as failure to heal rather than exacerbation discontinue therapy and treat appropriately if it occurs Prolonged use may increase risk of secondary infection, may mask acute infection, limit response to vaccines, and prolong or exacerbate viral infections avoid exposure to measles or chickenpox while receiving therapy not for the treatment of ocular herpes simplex, cerebral malaria, fungal infections, or viral hepatitis observe patients with latent tuberculosis closely restrict use in active tuberculosisĪcute myopathy reported with high dose corticosteroids, especially patients with neuromuscular transmission disorders Prolonged use may increase risk of Kaposi's sarcoma Occlusive dressings, prolonged use, application to large surface areas, or application to denuded skin, may increase percutaneous absorption, which may result in Cushing syndrome, glycosuria, and hyperglycemia Use lower potency in children may absorb proportionally larger amounts after topical application and may cause systemic effects Chronic topical corticosteroid therapy may interfere with growth and development in children
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